RANDOMIZED CONTROLLED TRIALS Laparoscopy in Combination with Fast Track Multimodal Management is the Best Perioperative Strategy in Patients Undergoing Colonic Surgery A Randomized Clinical Trial (LAFA-study)
نویسندگان
چکیده
Malaika S. Vlug, MD, PhD,∗ Jan Wind, MD, PhD,∗ Markus W. Hollmann, MD, PhD, DEAA,† Dirk T. Ubbink, MD, PhD,‡ Huib A. Cense, MD, PhD,§ Alexander F. Engel, MD, PhD,¶ Michael F. Gerhards, MD, PhD,∗∗ Bart A. van Wagensveld, MD, PhD,†† Edwin S. van der Zaag, MD,‡‡ Anna A.W. van Geloven, MD, PhD,§§ Mirjam A.G. Sprangers, PhD,¶¶ Miguel A. Cuesta, MD, PhD,∗∗∗ and Willem A. Bemelman, MD, PhD,* on behalf of the collaborative LAFA study group
منابع مشابه
Perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care (LAFA trial)
BACKGROUND Recent developments in large bowel surgery are the introduction of laparoscopic surgery and the implementation of multimodal fast track recovery programs. Both focus on a faster recovery and shorter hospital stay. The randomized controlled multicenter LAFA-trial (LAparoscopy and/or FAst track multimodal management versus standard care) was conceived to determine whether laparoscopic ...
متن کاملLaparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study).
OBJECTIVE To investigate which perioperative treatment, ie, laparoscopic or open surgery combined with fast track (FT) or standard care, is the optimal approach for patients undergoing segmental resection for colon cancer. SUMMARY BACKGROUND DATA Important developments in elective colorectal surgery are the introduction of laparoscopy and implementation of FT care, both focusing on faster rec...
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OBJECTIVE To evaluate the effect of laparoscopic or open colectomy with fast track or standard perioperative care on patient's immune status and stress response after surgery. METHODS Patients with nonmetastasized colon cancer were randomized to laparoscopic or open colectomy with fast track or standard care. Blood samples were taken preoperatively (baseline), and 1, 2, 24, and 72 hours after...
متن کاملCanadian Association of General Surgeons and American College of Surgeons Evidence-Based Reviews in Surgery. 24. Fast-track programs in colonic surgery
Objective: To compare fast-track (FT) perioperative programs for elective colonic resections with traditional care. Data source: Studies were identified by searching the Cochrane Library, MEDLINE and EMBASE; as well, relevant journals and conference proceedings and electronic links to related articles were hand-searched, and investigators were contacted. Study selection: Studies were included i...
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BACKGROUND & AIMS A fast-track program is a multimodal approach for patients undergoing colonic surgery that combines stringent regimens of perioperative care (fluid restriction, optimized analgesia, forced mobilization, and early oral feeding) to reduce perioperative morbidity, hospital stay, and cost. We investigated the impact of a fast-track protocol on postoperative morbidity in patients a...
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